Hasco-Lek,Lactulosum Hasco 2.5g/5ml 150ml

“Compound
5 ml of syrup contains:
active ingredient: lactulose 2.5 g.
excipients: orange flavor 240.016, citric acid monohydrate, purified water.

Dosage
Adults:
initial dose (first 3 days): 45 ml of syrup per day 1 time before breakfast or 15 ml of syrup 3 times a day before meals.
Maintenance dose: 15 ml of syrup on an empty stomach.
Children under 3 years old:
Initial dose: 5 to 15 ml of syrup per day.
The dose can then be gradually increased every 3 days until normal bowel movements are achieved.
Children:
initial dose: 2.5 ml of syrup per day.
The dose can then be gradually increased every 3 days until normal bowel movements are achieved.
Hepatic encephalopathy:
Adults: 120–180 ml of syrup in 3–4 doses.
Large doses used for this indication may cause diarrhea, so the dose should be adjusted so that the amount of loose stool does not exceed 2-3 per day.

Action
Lactulosum Hasco syrup contains the active ingredient lactulose, which is a synthetic disaccharide that is absorbed to a very small extent from the digestive tract. Lactulose is broken down in the colon into lactic, formic and acetic acids and carbon dioxide. These acids reduce the pH in the colon from 7 to 5 – 5.5 and have a local osmotic effect, causing water retention in the colon. As a result, feces become thinner and larger, and intestinal motility is stimulated.
In patients with hepatic encephalopathy, lactulose reduces ammonia toxicity. The acids formed as a result of the breakdown of lactulose lower the pH and affect the conversion of ammonia into non-absorbable and non-toxic ammonium ions, which leads to their retention in the colon and a decrease in the concentration of ammonia in the blood.

Indications
Lactulosum Hasco is used for:
constipation,
prevention and treatment of hepatic encephalopathy.

Contraindications
When not to use Lactulosum Hasco:
if you are hypersensitive to any of the ingredients of the drug.
if you have an intestinal obstruction.”

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