Ibulysin ADGC 400 mg 20,Zentiva Pharma

“Product composition
Active ingredients:
Ibuprofen DL-lysine 683.47 mg
Ibuprofen 400 mg
Excipients:
Microcrystalline cellulose, Croscarmellose sodium
talc, Highly dispersed silicon dioxide, Magnesium stearate (vegetable), Hypromellose, Macrogol 6000, Glycerin 85%

Application areas
The drug is an analgesic and antipyretic agent.
It is used for short-term symptomatic treatment of:
mild to moderate pain such as headaches, toothaches, menstrual cramps, and fever and pain associated with colds
the acute phase of migraine headaches with or without aura

Dosage
The usual dose is:
Adult
Initial dose: Take ibuprofen 200 or 400 mg (½ or 1 tablet of the drug).
If necessary, take an additional 200 mg or 400 mg of ibuprofen (½ or 1 tablet), but do not exceed a total dose of 1200 mg of ibuprofen (3 tablets) in 24 hours.
The interval between doses should not be less than 6 hours.
Children weighing 20 kg (from 6 years) and adolescents.
The drug is approved for use only in children weighing at least 20 kg. The maximum total daily dose of ibuprofen is 30 mg per kg of body weight, divided into 3-4 separate doses.
The interval between each dose should not be less than 6 hours.
Do not exceed the recommended maximum daily dose.
For children and adolescents, the following dosage recommendations apply:
Body weight: 20 – 29 kg.
Single dose of ibuprofen mg (tablets): 200 mg (½ tablet)
Maximum daily dose of ibuprofen, mg (tablets): 600 mg (1 ½ tablets).
Body weight: 30 – 39 kg.
Single dose of ibuprofen mg (tablets): 200 mg (½ tablet)
Maximum daily dose of ibuprofen, mg (tablets): 800 mg (2 tablets).
Body weight: 40 kg and more.
Single dose of ibuprofen, mg (tablets): 200–400 mg (½–1 tablet)
Maximum daily dose of ibuprofen, mg (tablets): 1200 mg (3 tablets).

Contraindications
The medicine should not be taken
if you are allergic to ibuprofen or any other ingredient of this medicine
if you have had shortness of breath, asthma, swelling of the nasal mucosa, angioedema or skin reactions after taking acetylsalicylic acid or other nonal anti-inflammatory/anti-inflammatory drugs (NSAIDs) in the past.
if you have unexplained blood disorders
if you have a history of existing or recurrent stomach/duodenal ulcers (peptic ulcers) or bleeding (at least two different episodes of proven ulcers or bleeding)
if you have a history of gastrointestinal bleeding or perforation in connection with previous treatment with NSAIDs.
if you have a bleeding in the brain (cerebrovascular haemorrhage) or other active bleeding
if you suffer from severe liver or kidney dysfunction
in the last 3 months of pregnancy
if you suffer from severe heart failure
if you suffer from severe dehydration (caused by vomiting, diarrhoea or insufficient fluid intake)
in children weighing less than 20 kg, as this dosage is not suitable due to the higher amount of active substance.”

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